Epigenetics

The field of epigenetics encompasses hereditary changes in gene expression that are not caused by changes (mutations) in the DNA sequence. Enzymatic modifications of DNA and chromatin (proteins for packaging DNA) determine the structure and activity of our genome and pass it on to the next generation of cells. Environmental influences may alter these processes, thereby triggering diseases. The effect of epigenetic changes is particularly well researched in cancer. In addition, therapies that target epigenetic enzymes are already in clinical use.

In the last few years, research gained considerable knowledge of epigenetic processes and increased our understanding of these mechanisms as pathways of environmental influences on the development of living organisms and their health. Today’s epigenetics bring together researchers from the fields of life sciences, chemistry, computer science and engineering, but also from social sciences and the humanities, e.g. ethics. Together they endeavour to answer the question of how behaviour and environmental influences affect gene expression in the long term and possibly even subsequent generations.

Among the working group’s top priorities is the promotion of networking between players and stakeholders in the field of epigenetics in Austria. We strive to facilitate interdisciplinary discussions and improve the visibility of the diverse medical, scientific, ethical, economic and social implications of this field of research.